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Categories » Medical Software » Pharmacology

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Respiratory Pharmacology  
Cat #: SB-24W
Respiratory Pharmacology

Price: AU$414.59 ( AU$456.05 Inc. GST)
USD $404.56 EUR €321.76 NZD $537.85

All Options: Multi-User Educational - Wins
Multi-User Educational - Mac
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This highly interactive program uses pulmonary function data obtained from guinea pig to teach the fundamental pharmacology of the airways.
 
1. AIMS, INTRODUCTION and METHODS sections of the program use a combination of text and high-resolution colour graphics to describe:
  • The aims and objectives of the program
  • the structure of the airways, the physiological control of bronchial smooth muscle tone pharmacology, airway smooth muscle receptor pharmacology, pathophysiology (asthma and COPD) and it’s treatment.
  • the guinea pig preparation and the apparatus used to monitor airway function.

2. EXPERIMENTS is the main section and allows the student to select, from a menu, to study the effects of various mediators and inhibitory agents in the normal and allergen-sensitized animals.

Normal Guinea Pig:

  • Vehicle (0.9ml saline);
  • Bronchoconstrictors (Histamine: 3 single doses and + mepyramine, + indomethacin + propranolol;
  • Acetylcholine (3 single doses and + atropine, + indomethacin, + propranolol;
  • Bradykinin (3 single doses and + indomethacin;)
  • Vagal Stimulation: (low frequency stimulation, LF + atropine, high frequency stimulation, HF + atropine);
  • Bronchodilators (bombesin treated: single dose, + epinephrine, + mepyramine)

Allergen-sensitized Guinea Pig:

  • Histamine, + mepyramine;
  • LTC4 + mepyramine, + montelucast;
  • Antigen (i.v.) + mepyramine; + mepyramine and montelucast.

For each experiment the display shows simultaneous traces of resistance, dynamic compliance and blood pressure which are presented in a form similar to that in the Mumed recording system. Each set of data is accompanied by self-assessment questions which demand interpretation of experimental data presented to them, and an understanding of the underlying control mechanisms. These student-centred activities make the program useful for self-directed learning or, in the ideal situation, it would be incorporated into a structured teaching programme and used with a teacher-designed workbook. It is envisaged that the program could be used in a number of ways: to better prepare students who will perform the practical at a later date; to debrief students after they have performed the practical; as a ‘fallback’ to provide data for students whose experiments were unsuccessful; as an alternative to the practical, though it should be remembered that different learning objectives may be achieved.

System Requirements: Windows: Intel Pentium II 450MHz or faster processor (or equivalent), 128MB of RAM; Microsoft Windows 98, Windows Me, Windows 2000, Windows XP or Windows Server 2003 Macintosh: PowerPC G3 500MHz or faster processor, 128MB of RAM; Mac OS X v.10.1.x, 10.2.x, 10.3.x, or 10.4.x

Recommended browser software: Windows: Internet Explorer; Macintosh: Safari or Firefox; Both: Adobe Flash Player plug-in, version 8 or higher.


 
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