COURSE OUTLINE: Introduction: Program Overview, Agarose Gel Electrophoresis, Immunofixation, Densitometry. Serum and Urine Patterns: Normal Pattern, Monoclonal Gammopathy, Inflammation, Protein Losing Disorders, Liver Disease, Other Serum Patterns, Other Urine Patterns. Cerebrospinal Fluid: Normal CSF,Abnormal CSF, Review of Disease States: Monoclonal Gammopathy, Inflammation, Liver Disease, CSF Oligoclonal Banding. Final Exam: Exam 1.

LEARNING OBJECTIVES:

• Describe the methods of agarose gel electrophoresis, immunofixation, and densitometry
• Name the clinical conditions most commonly associated with monoclonal gammopathy, and some key clinical features of each condition
• View an agarose gel, an immunofixation, and a densitometry and determine if a monoclonal gammopathy is present. If it is present, the user will be able to identify the immunoglobulin type
• View an agarose gel of serum, urine, or cerebrospinal fluid and identify the electrophoresis pattern (e.g., inflammation, liver disease, haemolysis, alpha-1 antitrypsin deficiency, tubular proteinuria, CSF oligoclonal banding, etc)

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System Requirements: Microsoft Internet Explorer version 6.0 or above, Windows Media Player 6.4, or above, Wins 98, or above, Pentium-class processor or above, Display capable of 800x600 or greater resolution, Display capable of displaying 16-bit colour, Sound card and speakers (recommended, not required), Printer.