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Genetic Engineering Single User Shipped in 7 days Cat.# CYT-4 $140.00   BUY 5 User Lab Pack Shipped in 7 days Cat.# CYT-4LP $250.00 Wins BUY     Mac BUY Site Licence Shipped in 7 days Cat.# CYT-4SL $410.00 Wins BUY     Mac BUY

You won't have to spend years in school to understand the concepts offered in Genetic Engineering. In this program, you'll see that organisms have a remarkable ability to manipulate DNA and transfer genes between organisms, keeping certain traits and dropping others.

A graphic, step-by-step examination of the procedures involved in transferring a human insulin gene to bacteria illustrate the techniques and processes of gene manipulation and transfer. With Genetic Engineering, you'll see genetic changes occurring from the cellular point of view.

Topics covered in this program include: DNA Composition and Its Function as Genetic Material; The Use of Natural Variation in Genes for Selective Breeding; Changes in Genes Through Mutation; A Step By Step Guide Through the Experimental Process of Genetic Engineering; Examples of modern Genetic Engineering in Microbes, Plants, and Animals; and the Applications of Genetic Engineering in Medicine and Gene Therapy.

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Medical GenetiX - Wins Single User Shipped in 4 days Cat.# MU-9 $ 45.45 BUY

Clinical and Molecular Aspects of Human Genetic Disorders

The explosion of knowledge in human genetics and applications of genetic technologies has resulted in a proliferation of concepts that are often difficult to impart in the limited context of lecture-based teaching. Furthermore, although we can engage students in discussions on the social and ethical issues in genetics, there is often reluctance to participate actively in a large group.

Medical Genetix is an innovative multimedia program for undergraduate medicine and biomedicine students that presents the concepts of human genetics and heredity within the clinical context of various chromosomal and single-gene disorders. The chromosomal disorders featured are trisomy 21 (Down syndrome), trisomy 18 (Edward syndrome) and Klinefelter syndrome; and the single-gene disorders are cystic fibrosis, Duchenne muscular dystrophy, Huntington disease and beta-thalassaemia.

Building on basic molecular biology - knowledge of the structure of DNA and genes, transcription and translation is assumed - Medical Genetix presents the science of genetics and heredity in a consistent modular framework across each of the clinical disorders. The three main modules and their sections are: Clinical Diagnosis - clinical features, family histories and pedigrees (for single-gene disorders), and molecular pathogenesis, the underlying molecular basis of the condition; Laboratory Diagnostics - DNA testing (for single-gene disorders), karyotyping (for chromosomal disorders), and pathology testing; and Counselling and Ethics, based on videos of counselling sessions related to a particular learning issue, with advice on counselling techniques and ethical issues.

Medical Genetix includes interactivity through a variety of approaches: drag-and-drop exercises, self-test questions and 'rollovers' that reveal more detail, as well as role-playing to explore ethical issues of relevance to genetic counselling. Comprehensive feedback and hints are given for the exercises and tests. An on-screen glossary of terms is also available at any time. Books, articles and websites are listed as references and for further reading.

Author: Dr Sylvia Metcalfe

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Introduction to Genetics CD-ROM - DOS/Wins Single User Shipped in 3 to 7 days Cat.# TS-20 $210.00 BUY 5 User Licence Shipped in 3 to 7 days Cat.# TS-20L1 $560.00 BUY 10 User Licence Shipped in 3 to 7 days Cat.# TS-20L2 $890.00 BUY

Designed to supplement undergraduate courses in genetics and biology, this package contains more than one hundred individual lessons covering topics from genetic ratios, mitosis and meiosis to DNA, RNA, and chromosome aberrations.

The lessons use a variety of techniques in presenting the material, including interactive tutorials, problem-solving drills, and definitions matching exercises. There are several levels of help available and feedback on incorrect responses is problem-specific.

Each Unit has a final Quiz with ten randomly selected questions so that students will rarely see the same sequence of questions no matter how many times they repeat the Quiz.

The package includes two helpful Instructor Utilities. The Text Reference System you use to add textbook references for each lesson if desired, and a Student Management System keeps records of student scores on the Unit Quiz programs.

Summary of Units

• Unit 1 - Mendel's Peas & Genetic Ratios Monohybrid Inheritance, Incomplete Dominance and Lethals, Dihybrid Inheritance, Trihybrid Inheritance, Genetic Interaction and Epistasis

• Unit 2 - Chromosomes, Mitosis, Meiosis Mitosis, Meiosis I & II

• Unit 3 - Sex Determination, Sex Linkage Sex-Linked Traits - Parts A & B, Sex-Influenced Traits, Sex-Limited Traits

• Unit 4 - Human Pedigrees Pedigrees, Family Probabilities, Risk Assessment, Consanguinity

• Unit 5 - Multiple Alleles & Blood Types Rabbit Coat Colours, ABO Blood Groups, Rh Blood Groups, Paternity

• Unit 6 - DNA, RNA & Proteins DNA, RNA: Transcription, RNA: Translation, Mutation

• Unit 7- Crossing Over & Mapping Linkage, Two-Point Mapping, Three-Point Mapping: Tutorials, Three-Point Mapping: Exercises, Neurospora

• Unit 8 - Euploidy & Aneuploidy Euploidy, Haploidy, Diploidy, and Triploidy, Euploidy: Polyploids, Aneuploidy: Monosomy, Aneuploidy: Trisomy

• Unit 9 - Chromosome Aberrations Breakage and Restitution Deletions, Duplications, Inversions and Rings, Translocations

• Management/Utilities Disk Student Management and Text Reference Systems

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Genetic Variation and Biotechnology Single User Shipped in 7 days Cat.# CYT-12 $ 90.00   BUY 10 User Network Shipped in 7 days Cat.# CYT-12N1 $180.00 Wins BUY     Mac BUY Site Licence Shipped in 7 days Cat.# CYT-12SL $440.00 Wins BUY     Mac BUY

Students explore genetic variation and human innovations that use genetic information to make new organisms. The human genome project, genetically engineered foods and ethics of gene transfer are also introduced.

Learners will:

• identify benefits or disadvantages to sexual or asexual reproductive strategies.

• disadvantages of inbreeding and benefits of selective breeding.

• distinguish between examples of inbreeding, selective breeding, and genetic engineering given illustrations and descriptions of organisms.

• distinguish between examples of sexual and asexual reproduction.

• predict beneficial or deleterious effects of selective breeding or inbreeding.

• predict the effect of different reproductive strategies (sexual, asexual, selective breeding) on variation or survival.

• sequence steps involved in producing recombinant DNA.

• apply a selective breeding strategy to create hypothetical offspring with a desired trait.

• sequence important steps for transferring a gene from one organism to another.

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PopGene CD-ROM - Wins Single User Shipped in 3 to 7 days Cat.# TS-22 $180.00 BUY 5 User Licence Shipped in 3 to 7 days Cat.# TS-22L1 $540.00 BUY 10 User Licence Shipped in 3 to 7 days Cat.# TS-22L2 $870.00 BUY

Population Genetics Simulations

PopGene is a collection of simulations commonly used in the study of population genetics, including:

• Hardy-Weinberg Equilibrium

• Multiple Allele Inheritance

• Multiple Loci Inheritance

• Natural Selection

• Genetic Drift

• Migration

• Mutation

• Inbreeding

The three part screen allows students to simultaneously view the simulation parameters, data plots and a dynamic graph of the results. Parameter values, the speed of the simulation, and the scale size of the graph and the graph type can be easily changed.

The operation of PopGene is simple and straightforward. Select a simulation and graph type, then start it using the default parameters or those you enter from the keyboard. As the simulation progresses, the outcome is shown in the results window and on the graph. Simulation parameters are easily changed, and the results may be saved to disk or printed.

Package includes a step-by-step tutorial of the Hardy-Weinberg simulation, mini-tutorials using the other models, and suggested exercises to be used in conjunction with the simulations.

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Fragile X Syndrome - Wins Single User Shipped in 4 days Cat.# MU-8 $ 20.00 BUY

Clinical and Molecular Aspects

Fragile-X Syndrome is a stand-alone interactive CD-ROM integrating the genetics and clinical features of fragile X syndrome.

It is produced by Associate Professor Sylvia Metcalfe from the University of Melbourne and Dr Jonathan Cohen from the Fragile X Alliance.

The program covers clinical diagnosis, laboratory diagnostics, and personal perspectives and includes high quality media such as videos, animations and interactive images from Australian families. Multiple choice questions, glossary of terms and references are also included.

This program will be useful for students studying human genetics, medical and biomedical courses, and for continuing professional education.

Authors: Associate Professor Sylvia Metcalfe, Dr Jonathan Cohen